Remote Observed Methadone Evaluation Phase 2 (ROME 2)

Michael L. Dennis, Belinda M. Willis
2024
Sonara (Prime PI: M. Giles)
National Institute on Drug Abuse (NIDA)
R44DA056259

This SBIR Phase II study continues to evaluate Sonara, a HIPAA-compliant web-application (app) with 2-way text messaging between patient and clinical team (counselor, nurse), that is designed to facilitate methadone take-home monitoring for two cohorts: 1) a group of long term clients who have plateaued at weekly take home (1 clinic visit per week with 6 days of take-homes) for 6 months or more and 2) a group of new clients as they first go onto weekly take home (with 1 or 2 clinic visits per week). The primary objectives are to increase retention in treatment while increasing their take home doses up to one clinic visit per month. The secondary objectives are to 1) examine the extent to which Sonara is associated with reduced substance use, craving, and withdrawal, as well as increased quality of life and 2) evaluate the extent to which the cost of Sonara is offset by reductions in the cost of transportation for in person dosing, other health care utilization, and/or quality of life adjusted years (QALY).