Research Projects, Program Evaluations, and Infrastructure Projects

Current Research Projects, Program Evaluations, and Infrastructure Projects

For a list of completed projects click here.

Lighthouse Institute – Current Project List (listed in ascending order)

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Pathways Partnership Platform (P3)

Barbara D. Estrada
2025
Chestnut Health Systems (PD: B. Estrada)
Indian Health Services (IHS) through Bureau of Indian Affairs

The Pathways Partnership Platform (P3) is an interagency cooperation and tribal partnerships for effective and innovative youth risk mitigation.

Substance Use Disorder Care Transitions

Joseph Glass
2025
Prime: Kaiser Foundation Hospitals (MPIs: J. Glass, E. Wong, & N. Hyun)
National Institute on Drug Abuse (NIDA)
R01DA062607

This study will characterize care transitions among patients within a large integrated health system that have a need for substance use disorder care and examine patient and clinician experiences with care transitions.

Diversity Supplement: Building a Lasting Foundation to Advance Actionable Research on Recovery Support Services for High Risk Individuals with Opioid Use Disorder: The Initiative for Justice and Emerging Adult Populations (JEAP)

Ashli J. Sheidow
2024
Chestnut Health Systems (PI: A. Sheidow)
National Institute on Drug Abuse (NIDA)
R24DA051950-S1

The goals of this diversity supplement to the JEAP Initiative are to (1) Conduct a systematic review of recovery capital measurement...

Evaluation of the DOJ-funded Phoenix Low Barrier Recovery Home (LBRH)

Dennis P. Watson, Justin S. Bell
2024
Cook County Health/Phoenix Recovery Support Services
Department of Justice (DOJ)

Phoenix Recovery Support Services will implement a 15-bed recovery housing program in Cook County, Illinois. Utilizing a Low Barrier Recovery Home Model (LBRHM), the program will prioritize providing stable housing to individuals regardless of their substance use.

Impacts of Access to Services for Alcohol Use Disorders in Older Adults

Joseph Glass
2024
Prime: University of Washington (MPIs: J. Glass & E. Wong)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
R21AA031045

This project will develop knowledge that will assess the problem of undertreatment of alcohol use disorders in older adults by examining access to care among Medicare Advantage enrollees.

PATH to Reducing Burnout among Peers Who Deliver Harm Reduction Services: Improving Workforce and Service System Outcomes through a Combined eLearning and Group Consultation Intervention

Dennis P. Watson
2024
Chestnut Health Systems (PI: D. Watson)
National Institute on Drug Abuse (NIDA)
R61DA061340

PATH (Peer Advanced Training in Harm reduction) is a workforce intervention that uses virtual education and case-based learning approaches to support PRSSs who deliver HR services.

Pathways to Wellness Recidivism Reduction Initiative – Virtual Recovery Environment (PWRRI VRE)

Barbara D. Estrada
2024
Chestnut Health Systems (PD: B. Estrada)
Bureau of Indian Affairs (BIA)
140A1619C0044

Community Care Coordinators will screen, refer to services, and coordinate treatment services for participants in two detention centers.

Qualitative synthesis of barriers and facilitators to an emergency department (ED)-based HF screening program

Dennis P. Watson
2024
Chestnut Health Systems (PIs: D. Watson & J. Dewey)
Emergency Medicine Foundation

The primary objective of our proposed study is to determine the barriers and facilitators to an emergency department (ED)-based heart failure (HF) screening program. This qualitative work will be used to help guide the development and implementation of an intervention.

Remote Observed Methadone Evaluation Phase 2 (ROME 2)

Michael L. Dennis, Belinda M. Willis
2024
Sonara (Prime PI: M. Giles)
National Institute on Drug Abuse (NIDA)
R44DA056259

This SBIR Phase II study continues to evaluate Sonara, a HIPAA-compliant web-application (app) with 2-way text messaging between patient and clinical team (counselor, nurse), that is designed to facilitate methadone take-home monitoring for two cohorts: 1) a group of long term clients who have plateaued at weekly take home (1 clinic visit per week with 6 days of take-homes) for 6 months or more and 2) a group of new clients as they first go onto weekly take home (with 1 or 2 clinic visits per week).

Screening, Brief Intervention, & Referral to Services (SBIRS) for School Personnel + Strengthening Parent Awareness, Rapport, and Communications (SPARC)

Ashli J. Sheidow, Tess K. Drazdowski
2024
Synergy Enterprises, Inc. (Prime PI: E. McCarthy)
Substance Abuse and Mental Health Services Administration (SAMHSA)
S-CHS-101123-05

This is part of the National Media Campaign to Prevent and Reduce Underage Drinking and Other Substances – STOP Act, and provides expert input into training and dissemination materials as part of the TTHY campaign.

Staffing and Supports for Implementing Cross-System Interventions with Peer Mentors (COSTARS)

Lisa Saldana
2024
Ohio State University (Prime PI: A. Bunger)
National Institute on Drug Abuse (NIDA)
R61/R33DA059893

This project tests the effectiveness of a supervision coaching strategy to promote workforce stability and START implementation while also creating conditions for strategy sustainment in Ohio’s child welfare system.

State Opioid Response (SOR) IV

Belinda M. Willis
2024
IL SUPR (Prime PD: K. Monahan)
Substance Abuse and Mental Health Services Administration (SAMHSA)
TI087748

The purpose of SOR-IV is to address escalating opioid misuse, opioid use disorder (OUD), and opioid-related overdose across Illinois.

Enhancement and Expansion of Treatment and Recovery Services for Adolescents, Transitional Aged Youth, and their Families (SR TREE)

Lora L. Passetti
2023
Chestnut Health Systems (PI: L. Passetti)
Substance Abuse and Mental Health Services Administration (SAMHSA)
H79TI083556

The purpose of the project is to enhance and expand comprehensive treatment, early intervention, and recovery support services for adolescents (ages 14-18) and their families with substance use disorders and/or co-occurring substance use and mental disorders.

ISTARR

2023
PHI (Prime PI: A. Mericle)
ISTARR-NIH
05491-AR67805

Pilot study to identify effective policies and practices for working with criminal legal system (CLS) clients who are receiving medicatin for opioid use disorder (MOUD) through a qualitative comparative case study of four recovery residences that are effectively and safely serviing the target population.

Leveraging parents and peer recovery supports to increase recovery capital in emerging adults with polysubstance use: Feasibility, acceptability, and scaling up of Launch

Tess K. Drazdowski
2023
Chestnut Health Systems (PI: T. Drazdowski)
National Institute on Drug Abuse (NIDA)
R34DA057639

The overarching objective is to investigate a scalable service that can be used in rural communities called Launch. Launch is an innovative adaptation of current evidence-based services for emerging adults (EAs; 18-26 years old) with polysubstance use, with a particular emphasis on increasing EA’s recovery capital. Recovery capital is the resources available to promote substance use recovery (e.g., vocational/educational skills, recovery-supportive community).

Minority AIDS Initiative – High Risk Populations (MAI-HRP)

Belinda M. Willis
2023
Haymarket Center (Prime PD: G. Soberanis)
Substance Abuse and Mental Health Services Administration (SAMHSA)
TI086833

The purpose of Haymarket’s MAI-HRP program is to increase engagement in care for racial and ethnic medically underserved individuals with substance use disorders (SUDs) and/or co-occurring SUDs and mental health conditions (COD) who are at risk for or living with HIV.

State Opioid Response (SOR) III

Belinda M. Willis
2023
IL SUPR (Prime PD: K. Monahan)
Substance Abuse and Mental Health Services Administration (SAMHSA)
TI085769

The purpose of SOR-III is to address escalating opioid misuse, opioid use disorder (OUD), and opioid-related overdose across Illinois.

Supporting Data-driven Decision-making to Support Substance Use Service Expansion Policies and to Prevent Overdoses (Data2Action Oregon or D2AOR)

Gracelyn Cruden
2023
Chestnut Health Systems (PI: G. Cruden)
National Institute on Drug Abuse (NIDA)
R61/R33 DA059163

This project’s goal is to increase the availability of user-friendly, relevant data to inform local decisions and policies across Oregon to ultimately connect individuals to a continuum of substance use services, prevent overdoses, and improve substance use policies.

Supportive Employment Program (SEP)

Belinda M. Willis
2023
Haymarket Center (Prime PD: A. Malson)
Substance Abuse and Mental Health Services Administration (SAMHSA)
SM88370

Haymarket SEP program intends to engage 238 adult Chicagoans over 5 years to overcome undertreated mental health and substance use disorders. Haymarket SEP will be data-driven and results-oriented, using the evidence-based Individual Placement and Support intervention model of Supported Employment and clinical interventions.

Youth Problem Gambling Prevention: Not a Chance (NAC)

Lora L. Passetti
2023
Chestnut Health Systems (PI: L. Passetti)
IL SUPR
43CD00055

The objective of this project is to evaluate a youth problem gambling prevention curriculum designed by Chestnut prevention staff.

Center for Dissemination and Implementation At Stanford Research Project 3: Addressing Barriers to Care for Substance Use Disorder

Joseph Glass
2022
Prime: Stanford University (Center PI: M. McGovern)
National Institute on Drug Abuse (NIDA)

This pragmatic trial addresses a critical scientific and public health gap: How can we intervene to address barriers to treatment among patients who are interested in seeking care for substance use disorders (SUDs)? This study will generate some of the first evidence to guide the implementation and effectiveness of care navigation interventions for SUD in routine practice.

Collaborative Hub for Emerging Adult Recovery Research (CHEARR)

Ashli J. Sheidow
2022
University of Connecticut (Prime PI: K. Zajac)
National Institute on Drug Abuse (NIDA)
R24DA057632

Emerging adults (16-25) are particularly affected by the opioid crisis.

Cook County Health MAT-PDOA

Belinda M. Willis
2022
Cook County Health and Hospital System (Prime PD: J. Watts)
Substance Abuse and Mental Health Services Administration (SAMHSA)
TI084335

Cook County Health’s MAT-PDOA program aims to increase and expand Medication-Assisted Treatment services for individuals diagnosed with opioid use disorder (OUD) by implementing a rapid access, low barrier, and high-capacity bridge clinic on Illinois Medical District Campus in Chicago.

Disrupting Social Risk Factors of Health to Improve Substance Use and Mental Health Outcomes for Parents in Rural Regions

Lisa Saldana
2022
Chestnut Health Systems (PI: L. Saldana)
National Institute on Drug Abuse (NIDA)
R01DA057556

This study evaluates how effectively the Just Care program helps parents involved in the child welfare system reduce their use of opioids or methamphetamines and improve their mental health.

Evaluation of Cook County Health's Community Health Workers for COVID Response and Resilient Communities Project Evaluation

Dennis P. Watson
2022
Cook County Health and Hospital System
U.S. Centers for Disease Control and Prevention
NU58DP006993

Cook County Health has been funded to train, deploy, and engage community health workers to work with target populations in Suburban Cook County. The goal of the program is to strengthen community resilience to fight COVID-19 by addressing health disparities in priority populations.

Grants for the Benefit of Homeless Individuals in Illinois (GBHI-IL)

Belinda M. Willis
2022
Haymarket Center (Prime PD: A. Holyk)
Substance Abuse and Mental Health Services Administration (SAMHSA)
TI082773

Haymarket GBHI project will expand substance use disorder (SUD) treatment and comprehensive services to 300 unique adults who are experiencing substance use disorder (SUD), serious mental illness (SMI), and homelessness.

Grants for the Benefit of Homeless Individuals in Virginia (GBHI-VA)

Lora L. Passetti
2022
Horizon Behavioral Health (Prime PD: D. Onafowokan)
Substance Abuse and Mental Health Services Administration (SAMHSA)
24LI0061

Horizon Behavioral Health received funds to serve homeless adolescents and their families in Virginia by providing trauma-informed outreach and engagement, screening and assessment for substance use and mental health disorders, substance use and mental health treatment, medication-assisted treatment for opioid use disorder, case management, and peer recovery support services.

Haymarket TCE-Special Project

Belinda M. Willis
2022
Cook County Health and Hospital System (Prime PD: K. Cathey)
Substance Abuse and Mental Health Services Administration (SAMHSA)
TI082139

Haymarket TCE-Special Project aims to assess adults with an opiate use disorder (OUD) and a co-occurring mental disorder by the expansion of MAT and intensive medication management by a team of direct care nurses. The TCE-Special Project intends to address medication noncompliance as part of a strategy to temper opiate and mental health treatment crises.

HEAL Connections: Partnering to Accelerate Research into Action (HEAL Connections)

Ashli J. Sheidow
2022
George Mason University (Prime PI: F. Taxman)
NIH HEAL Initiative
OT2OD034479

In response to the public health emergency of opioid misuse, addiction, and overdose, the NIH intends to deliver as quickly as possible the results of NIH’s Helping to End Addiction Long-term (HEAL) initiative research so communities and providers can make evidence-based decisions...

NW Violence Prev

Belinda M. Willis
2022
Northwestern University (Prime PI: M. Brook)
BC/BS-IL
60056521 CHS

The purpose of this study is to identify data-driven interventions to reduce rates of community violence in high-risk populations.

Refining and Pilot Testing a Decision Support Intervention to Facilitate Adoption of Evidence-Based Programs to Improve Parent and Child Mental Health (KORCA)

Gracelyn Cruden
2022
Chestnut Health Systems (PI: G. Cruden)
National Institute of Mental Health (NIMH)
K01MH128761

This project aims to support groups deciding which evidence-based interventions and other innovations to implement in their communities and service systems.

Regional Partnership Grant (RPG): Connecticut Strengthening Families Together (CT SFT)

Michael L. Dennis
2022
Connecticut DCF (Prime PI: K. Robles)
ACF Children's Bureau
90CU0127-01-00

The new program, Multidimensional Family Treatment and Recovery (MDFTR), works with parents/caregivers who have substance use disorders both to address their SUD directly and indirectly to prevent or reduce child maltreatment and out-of-home placement for children under age six (prenatal through 5 years inclusive).

Scaling up eConnect in Juvenile Probation Settings: A Hybrid Implementation-Effectiveness Trial of a Digital Suicide Risk/Behavior Identification and Linkage-to-Treatment System (e-Connect-IN)

Barbara D. Estrada, Michael L. Dennis
2022
Columbia University (Prime PI: K. Elkington)
National Institute of Mental Health (NIMH)
R01MH130845

The purpose of the project is to develop and test a software application that seeks to improve delivery of mental health services and reduce suicide risk in adolescents transitioning out of the juvenile justice system.

Comparing Two Federal Financing Strategies on Treatment Penetration and Sustainment

Lora L. Passetti
2021
RAND Corporation (Prime PI: A. Dopp)
National Institute on Drug Abuse (NIDA)
R01 DA051545

This project will compare the effects of two SAMHSA grant mechanisms (i.e., financing strategies), which supported the adoption of an EBP for adolescent SUD through either organization-focused or state-focused granting of funds.

Comprehensive Opioid Recovery Centers (CORC)

Belinda M. Willis
2021
Haymarket Center (Prime PD: K. Fletcher)
Center for Substance Abuse Treatment (CSAT)
TI083080

The goal of Haymarket’s CORC program is to reduce opioid-related overdoses by 1) expanding outreach visits to 500 persons; 2) expanding treatment, including using MAT; and 3) expanding comprehensive recovery services to 250 participants.

Enhancing Substance Use Treatment Services to Decrease Dropout and Improve Outpatient Treatment Utilization in Emerging Adults (P2P)

Ashli J. Sheidow
2021
University of Connecticut (Prime PI: K. Zajac)
National Institute on Drug Abuse (NIDA)
R01DA051671

Emerging adults (EAs; 18-25) have the highest rates of substance use disorders and are particularly affected by the opioid crisis. They also tend to drop out of treatment more frequently and use services less than other age groups, leading to worse outcomes like continued substance use, incarceration, and overdose.

Evaluation of Cook County Health's Comprehensive Opioid, Stimulant, and Substance Use Program (COSSUP)

Dennis P. Watson
2021
Cook County Health and Hospital System
Department of Justice (DOJ)
15PBJA-22-GG-04397-COAP

The primary objectives of this project are to (1) evaluate the Cook County Recovery Learning and Action Network (LAN) as a community coalition with a goal for actionable change and (2) conduct an implementation feasibility evaluation of a real-time recovery housing inventory.

Screen 4 Success

Barbara D. Estrada
2021
Synergy Enterprises, Inc. (Prime PD: C. PoVey)
Substance Abuse and Mental Health Services Administration (SAMHSA)
HHSS277201700001C

LI will develop a web-based cloud application to provide a self-screening and referral management service to people referred by the “Talk. They Hear You.” (TTHY) mobile application and national media campaign.

Building a Lasting Foundation to Advance Actionable Research on Recovery Support Services for High Risk Individuals with Opioid Use Disorder: The Initiative for Justice and Emerging Adult Populations (JEAP)

Ashli J. Sheidow
2020
Chestnut Health Systems (PI: A. Sheidow)
National Institute on Drug Abuse (NIDA)
R24DA051950

The JEAP Initiative will advance research on the efficacy/effectiveness of peer recovery supports and recovery residences for public-system involved emerging adults...

Cook County Offender Reentry Program (CCORP)

Belinda M. Willis
2020
Cook County Health and Hospital System (Prime PD: S. Elder)
Substance Abuse and Mental Health Services Administration (SAMHSA)
TI080942

The purpose of this program is to expand and/or enhance substance abuse and mental health treatment and related recovery and reentry services to female adult offenders returning to the community from incarceration for criminal offenses.

Family Treatment Drug Court in Virginia (FTDC-VA)

Lora L. Passetti
2020
Horizon Behavioral Health (Prime PD: J. Girandola)
Substance Abuse and Mental Health Services Administration (SAMHSA)
24LI0041

Horizon Behavioral Health received funds to expand its Family Treatment Drug Court (FTDC) in Bedford County, Virginia. It is hypothesized that FTDC participants will show decreased rates of substance use, mental health problems, and engagement in illegal activities between intake to FTDC and 6 months post-intake.

Family-based Recovery Support Service Network for Youth OUD (CoARS)

Ashli J. Sheidow
2020
Partnership to End Addiction (Prime PI: A. Hogue)
National Institute on Drug Abuse (NIDA)
R24DA051946

The Consortium on Addiction Recovery Science (CoARS) is funded by NIDA and coordinated by Dr. Aaron Hogue (PI).

Linking a Pediatric Healthcare Advance with a Task-Shifting Approach to Optimize Juvenile Justice Outcomes (LEAP)

Ashli J. Sheidow
2020
Oregon Social Learning Center (Prime PI: M. McCart)
National Institute on Drug Abuse (NIDA)
R01DA050669

Juvenile justice serves over a million cases annually and is a primary source for substance use and behavior treatment referrals

Reducing Opioid and Other Drug Use in Justice-Involved Emerging Adults using Paraprofessional Coaches (with and without Lived Experience) to Deliver Effective Services in a Non-Treatment Setting (PEERS)

Tess K. Drazdowski
2020
Chestnut Health Systems (PI: T. Drazdowski)
National Institute on Drug Abuse (NIDA)
K23DA048161

The ultimate aim of this research program is to improve provision of evidence-based practices (EBPs) to emerging adults (EAs) with substance use (SU) problems and criminal legal system (CLS) involvement. To that end, this project investigates if using similar-aged paraprofessional coaches can effectively engage this underserved community in SU services.

Justice Community Opioid Innovation Network (JCOIN): Improving Retention across the OUD Service Cascade upon Reentry from Jail using Recovery Management Checkups (RMC-A) Experiment

Michael L. Dennis, Christine Grella
2019
Chestnut Health Systems (MPIs: M. Dennis & C. Grella)
National Institute on Drug Abuse (NIDA)
UG1DA050065

Jails provide an optimal setting for intervening with individuals with opioid use disorders (OUD), given the high volume of offenders with OUD, and their high risk of relapse to opioids following their release to the community. It is imperative that individuals with OUD are linked to community-based medication assisted treatment (MAT) upon their re-entry, as well as receive support for their ongoing treatment retention and recovery.

Preventing Parental Opioid and/or Methamphetamine Addiction within DHS-Involved Families (FAIR)

Lisa Saldana
2019
Chestnut Health Systems (PI: L. Saldana)
National Institute on Drug Abuse (NIDA)
UH3DA050193

This Hybrid Type II effectiveness-implementation trial examines the effectiveness of an evidence-based program – Families Actively Improving Relationships (FAIR) when adapted for upstream prevention (PRE-FAIR) of opioid and or methamphetamine use disorder.

e-Connect NY

Michael L. Dennis
2017
Columbia University (Prime PI: K. Elkington)
National Institute of Mental Health (NIMH)
R01 MH113599

The purpose of the project was to develop and test a software application that seeks to improve delivery of mental health services and reduce suicide risk in adolescents transitioning out of the juvenile justice system.

Recovery Initiation and Management after Overdose (RIMO) Experiment

Christine Grella
2017
Chestnut Health Systems (PI: C. Grella)
National Institute on Drug Abuse (NIDA)
R21/R33 DA045774

Emergency responders, including paramedics, fire fighters, and police, routinely come into contact with individuals who have overdosed and play a critical role in administering naloxone to reverse opioid-related overdose. However, mechanisms to link these individuals to medication-assisted treatment (MAT) following an overdose are lacking. This study targets individuals in Chicago who have received naloxone administered by first responders within the past week to reverse an overdose, but who have not entered into MAT.

Recovery Management Checkups for Primary Care (RMC-PC) Experiment

Dennis P. Watson
2017
Chestnut Health Systems (PI: D. Watson)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
R01 AA24440

Screening and Brief Intervention (SBI) in primary care for risky adult alcohol use has been demonstrated effective in reducing use among heavy alcohol users. While the process also identifies 5-10% of the patients who have substance use disorders (SUD) that require referral to alcohol and other drug (AOD) treatment, the most recent meta-analysis indicates that the procedures had little to no effect on actual treatment linkage and utilization.

Pathway to Wellness Recidivism Reduction Initiative (PWRRI)

Barbara D. Estrada
2014
Chestnut Health Systems (PD: B. Estrada)
Bureau of Indian Affairs (BIA)
140A1619C0044

In 2014, the Bureau of Indian Affairs (BIA) and the Office of Justice Services (OJS) created the Diversion to Re-entry Division (DRD) within the Tribal Justice Support (TJS) Directorate to address the need for reducing criminal recidivism in tribal communities through identification of need and risk, referral, treatment, re-entry and tracking offenders along a cascade of justice services.

Saldana Collaborations

Lisa Saldana
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