Christine Grella, PhD

Senior Research Scientist

Senior Research Scientist

NIMH Postdoctoral Fellow University of California—Los Angeles, 1986–1989 (Mental Health Services Research), University of California—Santa Cruz, PhD, 1985 (Social Psychology), and University of California—Los Angeles, BA, 1977 (Psychology)

Specialty areas: SUD treatment access and utilization; SUD treatment effectiveness; SUD and mental health comorbidity; gender and SUD treatment; longitudinal evaluation of substance use treatment and trajectories


Dr. Christine E. Grella is a Senior Research Scientist at Lighthouse Institute (2017–present). She held a faculty appointment in the Department of Psychiatry and Biobehavioral Sciences at the University of California—Los Angeles from 1992–2018 (currently Professor Emerita) and was Director of the UCLA Integrated Substance Abuse Programs (2012–2017). She received her doctorate in Social Psychology from the University of California—Santa Cruz in 1985. Dr. Grella conducts research on substance use and treatment outcomes among youth and adults, with a focus on gender differences and health disparities in access to and outcomes of treatment. Her research has examined service access, utilization, and outcomes of participation in multiple service delivery systems, including substance use disorder treatment, mental health, child welfare, health services, HIV services, and criminal justice systems. Dr. Grella has led several longitudinal cohort studies, over a dozen evaluation studies of SAMHSA-funded treatment interventions for individuals with substance use and/or mental health disorders, and epidemiological studies using national survey data on treatment need and utilization. She serves on several scientific and community advisory boards related to behavioral health services and is a frequent reviewer for NIH/NIDA.

Selected Publications: 

Grella, C. E., Ostlie, E., Watson, D. P., Scott, C. K, Carnevale, J., & Dennis, M. L. (2022). Scoping review of interventions to link individuals to substance use services at discharge from jail. Journal of Substance Abuse Treatment. 108718. PMCID: PMC9167253. https://doi.org/10.1016/j.jsat.2021.108718

Grella, C. E., & Stein, J. A. (2013). Remission from substance dependence: Differences between individuals in a general population longitudinal survey who do and do not seek help. Drug and Alcohol Dependence, 133, 146–153. PMCID: PMC3786033. https://doi.org/10.1016/j.drugalcdep.2013.05.019

Grella, C. E., Needell, B. N., Shi, Y., & Hser, Y. I. (2009). Do drug treatment services predict reunification outcomes of mothers and their children in child welfare? Journal of Substance Abuse Treatment, 36(3), 278–293. PMCID: PMC2848488. https://doi.org/10.1016/j.jsat.2008.06.010

See all Publications

 

Selected Grants and Contracts: 

Multiple Principal Investigator: Improving Retention Across the OUD Service Cascade Upon Re-entry from Jail Using Recovery Management Checkups Adaptive (RMC-A) (MPIs: Dennis, Grella. NIH/NIDA: UG1-DA050065, 2019–2024)

Principal Investigator: Recovery Initiation and Management after Overdose (RIMO) Experiment (NIH/NIDA: R21/R33-DA045774, 2017–2023; NCE: 2024)

Principal Investigator: Gender Differences in a Long-term Follow-up of Opiate Users (NIH/NIDA: R01-DA015390, 2004–2010)

Co-Investigator: A Natural History of Narcotics Addiction: A 33-Year Follow-up (PI: Hser. NIH/NIDA: R01-DA09169, 1995–1999)

Appointments and Awards: 

Professor-in-Residence, Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience & Human Behavior, University of California, Los Angeles: 1992–2018

Related Links:

Christine Grella Google Scholar

Research Projects

Justice Community Opioid Innovation Network (JCOIN): Improving Retention across the OUD Service Cascade upon Reentry from Jail using Recovery Management Checkups (RMC-A) Experiment

Michael L. Dennis, Christine Grella
2019
Chestnut Health Systems (MPIs: M. Dennis & C. Grella)
National Institute on Drug Abuse (NIDA)
UG1DA050065

Jails provide an optimal setting for intervening with individuals with opioid use disorders (OUD), given the high volume of offenders with OUD, and their high risk of relapse to opioids following their release to the community. It is imperative that individuals with OUD are linked to community-based medication assisted treatment (MAT) upon their re-entry, as well as receive support for their ongoing treatment retention and recovery.

Recovery Initiation and Management after Overdose (RIMO) Experiment

Christine Grella
2017
Chestnut Health Systems (PI: C. Grella)
National Institute on Drug Abuse (NIDA)
R21/R33 DA045774

Emergency responders, including paramedics, fire fighters, and police, routinely come into contact with individuals who have overdosed and play a critical role in administering naloxone to reverse opioid-related overdose. However, mechanisms to link these individuals to medication-assisted treatment (MAT) following an overdose are lacking. This study targets individuals in Chicago who have received naloxone administered by first responders within the past week to reverse an overdose, but who have not entered into MAT.

Publications

Kahn, J. H., Hart, M. K., Watson, D. P., Allen, C. B., Singh, R. R., Grella, C. E., & Dennis, M. L. (2025). Recent incarceration and minoritized racial status as barriers to the effectiveness of Recovery Management Checkups. Substance Abuse Treatment, Prevention, and Policy, 20(53). https://doi.org/10.1186/s13011-025-00684-4

Kahn, J. H., Hart, M. K., Watson, D. P., Allen, C. B., Singh, R. R., Grella, C. E., & Dennis, M. L. (2025). Recent incarceration and minoritized racial status as barriers to the effectiveness of Recovery Management Checkups. Substance Abuse Treatment, Prevention, and Policy, 20(53). https://doi.org/10.1186/s13011-025-00684-4